This panel examines the diverse ways in which the Bible was interpreted and deployed within the literary, theological and artistic cultures of Eastern Christianity from the medieval to the early modern period. Bringing together case studies from Armenian, Greek, Arabic, and Slavonic traditions, the panel emphasizes the Bible as a site of continual negotiation, where questions of authority, hermeneutics, and cultural identity were worked out through processes of translation, commentary, and citation. By foregrounding the philological and exegetical practices of different Eastern Christian communities, the panel explores how biblical authority was mediated through specific intellectual traditions. Through comparative lenses, the panel interrogates how Eastern Christian authors mobilized the Bible not only as a repository of divine revelation, but as a flexible discursive resource for constructing theological argumentation, negotiating cultural boundaries, and asserting communal authority. By situating these practices within their cross-cultural contexts, the panel seeks to illuminate the dynamics of textual transmission and hermeneutical appropriation that shaped the reception of Scriptures across Eastern Christianity. As such, it opens space for dialogue between traditionally separate fields of Armenian, Byzantine, Arabic, and Slavonic studies, and proposes a broader framework for understanding how the Scriptures functioned as a transregional medium of intellectual and theological exchange.